Development of JCDS, a computational dosimetry system at JAEA for boron neutron capture therapy

Development of JCDS, a computational dosimetry system at JAEA for boron neutron capture therapy

An investigation into the potential applicability of gel dosimeters for dosimetry in boron neutron capture therapy

Background: The aim of this work was to establish how well gel dosimeters performed, as substitutes for brain tissue compared with standard phantom materials such as water, polymethyl-methacrylate (or PMMA), A150 plastic and TE- liquid phantom material for dosimetry of neutron beams in boron neutron capture therapy. Materials and Methods: Thermal neutron fluence, photon dose and epithermal neu...

The Dosimetry Calculation for Boron Neutron Capture Therapy

BNCT incorporates the targeting principles of chemotherapy and the anatomical localization principles of conventional radiotherapy but with three distinct advantages:  Current boron compounds at the required concentrations are non-toxic.  The time interval between drug administration and neutron irradiation can be chosen to maximize the concentration differential between tumour and normal tis...

Dosimetry Impact of Boron and Its Carriers Structure at Boron Neutron Capture Therapy of a Brain Tumor; A Sim- ulation Study

Introduction: Boron neutron capture therapy (BNCT) is a method of cancer treatment and potentially, two borono-L-phenylalanine (BPA) and sodium borocaptate (BSH) are used in BNCT as common boron carriers. Some previous studies have shown that the dose rate is directly related to boron concentration in the tissue. This study aimed to simulate the structure of boron carriers and brain tumor compo...

Dosimetry Impact of Boron and Its Carriers Structure at Boron Neutron Capture Therapy of a Brain Tumor; A Sim- ulation Study

Introduction: Boron neutron capture therapy (BNCT) is a method of cancer treatment and potentially, two borono-L-phenylalanine (BPA) and sodium borocaptate (BSH) are used in BNCT as common boron carriers. Some previous studies have shown that the dose rate is directly related to boron concentration in the tissue. This study aimed to simulate the structure of boron carriers and brain tumor compo...